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Mouse Anti-PRRG1 Recombinant Antibody (1C7) (CBMAB-P3044-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1C7
Antibody Isotype
IgG2a, κ
Application
ELISA, IF, IHC-P, WB

Basic Information

Immunogen
PRRG1 (NP_000941.1, 22-81 aa) partial recombinant protein with GST tag. Immunogen sequence: NGFFEEIRQG NIERECKEEF CTFEEAREAF ENNEKTKEFW STYTKAQQGE SNRGSDWFQF
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 22-81

Target

Full Name
proline rich Gla (G-carboxyglutamic acid) 1
Introduction
PRRG1 is a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins.
Entrez Gene ID
5638
UniProt ID
O14668
Alternative Names
PRGP1
Cellular Location
Membrane
Topology
Extracellular: 21-83
Helical: 84-106
Cytoplasmic: 107-218
PTM
Gla residues are produced after subsequent post-translational modifications of glutamate by a vitamin K-dependent gamma-carboxylase.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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