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Mouse Anti-PRRG2 Recombinant Antibody (CBYC-P667) (CBMAB-P3046-YC)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYC-P667
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
PRRG2 (NP_000942, 50-109 aa) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
proline rich Gla (G-carboxyglutamic acid) 2
Introduction
PRRG2 is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein.
Entrez Gene ID
UniProt ID
Alternative Names
PRGP2
Cellular Location
Cell membrane
Topology
Extracellular: 50-109
Helical: 110-130
Cytoplasmic: 131-202
PTM
Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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