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Mouse Anti-PSMB11 Recombinant Antibody (A-5) (CBMAB-P3163-YC)

Provided herein is a Mouse monoclonal antibody against Human Proteasome Subunit Beta 11. The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all PSMB11 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
A-5
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Proteasome Subunit Beta 11
Introduction
PSMB11 (Proteasome Subunit Beta 11) is a protein coding gene. Diseases associated with PSMB11 include Thymus Cancer. Among its related pathways are Cell Cycle, Mitotic andRET signaling. Gene Ontology annotations related to this gene include threonine-type endopeptidase activity. An important paralog of the gene is PSMB8.
Entrez Gene ID
Human122706
Mouse73902
Rat290206
UniProt ID
HumanA5LHX3
MouseQ8BG41
RatM0R7C4
Alternative Names
BETA5T
Function
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Incorporated instead of PSMB5 or PSMB8, this unit reduces the chymotrypsin-like activity of the proteasome (By similarity).
Plays a pivotal role in development of CD8-positive T cells (By similarity).
Biological Process
CD8-positive, alpha-beta T cell differentiationIEA:Ensembl
Proteasomal protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
ProteolysisManual Assertion Based On ExperimentIDA:MGI
T cell differentiation in thymusIEA:Ensembl
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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