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Mouse Anti-PSMC4 Recombinant Antibody (CBYC-P708) (CBMAB-P3205-YC)

Provided herein is a Mouse monoclonal antibody against Human Proteasome 26S subunit, ATPase 4. The antibody can be used for immunoassay techniques, such as ICC, IF, IHC, WB.
See all PSMC4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYC-P708
Antibody Isotype
IgG2a, κ
Application
ICC, IF, IHC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
proteasome (prosome, macropain) 26S subunit, ATPase, 4
Introduction
PSMC4 (Proteasome 26S Subunit, ATPase 4) is a protein coding gene. Diseases associated with PSMC4 include Myotonia. Among its related pathways are Cell Cycle, Mitotic andRET signaling. Gene Ontology annotations related to this gene include hydrolase activity and four-way junction helicase activity.
Entrez Gene ID
5704
UniProt ID
P43686
Alternative Names
MIP224; RPT3; S6; TBP-7; TBP7
Function
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
Biological Process
Blastocyst developmentIEA:Ensembl
Proteasome-mediated ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
ProteolysisManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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