Mouse Anti-PSMD1 Recombinant Antibody (A-3) (CBMAB-P3213-YC)

Name: Mouse Anti-PSMD1 Recombinant Antibody (A-3)
SKU: CBMAB-P3213-YC
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

A-3

Application

WB, IP, IF, ELISA

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Proteasome 26S Subunit, Non-ATPase 1

Introduction

PSMD1 (Proteasome 26S Subunit, Non-ATPase 1) is a protein coding gene. Among its related pathways are Cell Cycle, Mitotic and RET signaling. Gene Ontology annotations related to this gene include binding and enzyme regulator activity.

Entrez Gene ID

Human	5707
Mouse	70247
Rat	83806

UniProt ID

Human	Q99460
Mouse	Q3TXS7
Rat	O88761

Alternative Names

P112; Rpn2; S1

Function

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.

Biological Process

Proteasome-mediated ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Regulation of protein catabolic processIEA:InterPro

Cellular Location

azurophil granule lumen
cytosol
extracellular region
membrane
nucleoplasm
nucleus
proteasome accessory complex
proteasome complex
proteasome regulatory particle
proteasome regulatory particle, base subcomplex
proteasome storage granule

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-PSMD1 Recombinant Antibody (CBLQP-010) (CAT#: CBMAB-2068CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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