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Mouse Anti-PSMD2 Recombinant Antibody (1A12) (CBMAB-P3225-YC)

Provided herein is a Mouse monoclonal antibody against Human Proteasome 26S Subunit, Non-ATPase 2. The antibody can be used for immunoassay techniques, such as IF, WB.
See all PSMD2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1A12
Antibody Isotype
IgG2a
Application
IF, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
Introduction
PSMD2 (Proteasome 26S Subunit, Non-ATPase 2) is a protein coding gene. Among its related pathways are Cell Cycle, Mitotic and RET signaling. Gene Ontology annotations related to this gene include binding and enzyme regulator activity.
Entrez Gene ID
5708
UniProt ID
Q13200
Alternative Names
RPN1; TRAP2; S2; P97
Function
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
Biological Process
Proteasome-mediated ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Regulation of protein catabolic processIEA:InterPro
Cellular Location
cytosol
extracellular exosome
extracellular region
ficolin-1-rich granule lumen
membrane
nucleoplasm
nucleus
proteasome accessory complex
proteasome complex
proteasome regulatory particle
proteasome regulatory particle, base subcomplex
proteasome storage granule
secretory granule lumen
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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