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Mouse Anti-PSMD6 Recombinant Antibody (1C1) (CBMAB-A7146-LY)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
1C1
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
PSMD6 (NP_055629, 292 a.a. ~ 389 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
Entrez Gene ID
UniProt ID
Alternative Names
KIAA0107; Rpn7; S10; SGA-113M; p44S10
Function
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Biological Process
Proteasome-mediated ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytosol
extracellular region
ficolin-1-rich granule lumen
nucleoplasm
proteasome accessory complex
proteasome complex
proteasome regulatory particle
secretory granule lumen
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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