Mouse Anti-PSMD7 Recombinant Antibody (CBYC-P719) (CBMAB-P3238-YC)

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CBYC-P719
Application
ELISA, WB
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.2, 0.09% sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-325
More Infomation

Target

Full Name
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
Introduction
PSMD7 (Proteasome 26S Subunit, Non-ATPase 7) is a protein coding gene. Diseases associated with PSMD7 include Hereditary Renal Cell Carcinoma. Among its related pathways are Cell Cycle, Mitotic and RET signaling. Gene Ontology annotations related to this gene include protein homodimerization activity. An important paralog of the gene is EIF3F.
Entrez Gene ID
UniProt ID
Alternative Names
MOV34; P40; Rpn8; S12
Function
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Biological Process
Proteasome-mediated ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytosol
extracellular exosome
extracellular region
ficolin-1-rich granule lumen
membrane
nucleoplasm
nucleus
proteasome complex
proteasome regulatory particle
secretory granule lumen
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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