Mouse Anti-PTP4A1 Recombinant Antibody (29) (CBMAB-P3402-YC)

Name: Mouse Anti-PTP4A1 Recombinant Antibody (29)
SKU: CBMAB-P3402-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

Application

ELISA, WB, IHC-P, IF, ICC, IP

Immunogen

Full length

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Protein tyrosine phosphatase type IVA, member 1

Introduction

PTP4A1 is a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis.

Entrez Gene ID

Human	7803
Mouse	19243
Rat	29463

UniProt ID

Human	Q93096
Mouse	Q63739
Rat	Q78EG7

Alternative Names

HH72; PRL-1; PRL1; PTP(CAAX1); PTPCAAX1

Function

Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis.

Biological Process

Cell cycleIEA:UniProtKB-KW
Positive regulation of cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Protein dephosphorylationIEA:InterPro

Cellular Location

Cell membrane
Early endosome
Endoplasmic reticulum
Cytoplasm
Cytoplasm, cytoskeleton, spindle
Nucleus
And mitotic spindle.

PTM

Farnesylated. Farnesylation is required for membrane targeting. Unfarnesylated forms are shifted into the nucleus.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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