Mouse Anti-RAB22A Recombinant Antibody (CBCNR-015) (CBMAB-R0756-CN)

Name: Mouse Anti-RAB22A Recombinant Antibody (CBCNR-015)
SKU: CBMAB-R0756-CN
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

CBCNR-015

Application

ELISA, WB

Immunogen

RAB22A (H15710, aa. 1-194) full-length recombinant protein with GST tag

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

1× PBS, pH 7.2

More Infomation

Target

Full Name

RAB22A, member RAS oncogene family

Introduction

The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and interaction between endosomal compartments. [provided by RefSeq, Jul 2008]

Entrez Gene ID

57403

UniProt ID

Q9UL26

Alternative Names

RAB22A, Member RAS Oncogene Family; Rab-22; Ras-Related Protein Rab-22A; GTP-Binding Protein RAB22A; RAB22;

Function

Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes (PubMed:16537905).
Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth (PubMed:21849477).
Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form (PubMed:16537905).

Biological Process

Biological Process endocytosisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process endosome organizationManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of vesicle sizeManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Endosome membrane
Cell membrane
Early endosome
Late endosome
Cell projection, ruffle
Cytoplasmic vesicle
Cytoplasmic vesicle, phagosome
Cytoplasmic vesicle, phagosome membrane
Recruited to phagosomes containing S.aureus or M.tuberculosis.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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