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Mouse Anti-RAB22A Recombinant Antibody (CBCNR-015) (CBMAB-R0756-CN)

This product is a Mouse antibody that recognizes RAB22A. The antibody CBCNR-015 can be used for immunoassay techniques such as: ELISA, WB.
See all RAB22A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNR-015
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
RAB22A (H15710, aa. 1-194) full-length recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
1× PBS, pH 7.2

Target

Full Name
RAB22A, member RAS oncogene family
Introduction
The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and interaction between endosomal compartments. [provided by RefSeq, Jul 2008]
Entrez Gene ID
57403
UniProt ID
Q9UL26
Alternative Names
RAB22A, Member RAS Oncogene Family; Rab-22; Ras-Related Protein Rab-22A; GTP-Binding Protein RAB22A; RAB22;
Function
Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes (PubMed:16537905).
Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth (PubMed:21849477).
Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form (PubMed:16537905).
Biological Process
Biological Process endocytosisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process endosome organizationManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of vesicle sizeManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Endosome membrane
Cell membrane
Early endosome
Late endosome
Cell projection, ruffle
Cytoplasmic vesicle
Cytoplasmic vesicle, phagosome
Cytoplasmic vesicle, phagosome membrane
Recruited to phagosomes containing S.aureus or M.tuberculosis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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