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Mouse Anti-RAB28 Recombinant Antibody (2C6) (CBMAB-R0794-CN)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2C6
Application
WB, IP, ELISA

Basic Information

Specificity
Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
RAB28, member RAS oncogene family
Introduction
This gene encodes a member of the Rab subfamily of Ras-related small GTPases. The encoded protein may be involved in regulating intracellular trafficking. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 9 and X. [provided by RefSeq, Apr 2009]
Entrez Gene ID
9364
UniProt ID
P51157
Alternative Names
RAB28, Member RAS Oncogene Family; Ras-Related Protein Rab-28; CORD18;
Biological Process
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process toxin transportIEA:Ensembl
Cellular Location
Cell membrane
Cytoplasm, cytoskeleton, cilium basal body
Expressed in the basal body and ciliary rootlet of the photoreceptors.
Involvement in disease
Cone-rod dystrophy 18 (CORD18):
A form of cone-rod dystrophy, an inherited retinal dystrophy characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual acuity and sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision occurs earlier than in retinitis pigmentosa, due to cone photoreceptors degenerating at a higher rate than rod photoreceptors.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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