Mouse Anti-RABEP1 Recombinant Antibody (20/Rabaptin-5) (CBMAB-R0961-CN)

Name: Mouse Anti-RABEP1 Recombinant Antibody (20/Rabaptin-5)
SKU: CBMAB-R0961-CN
Rating: 5 (1 reviews)

See all RABEP1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

20/Rabaptin-5

Application

WB, IF

Immunogen

Human Rabaptin-5 aa. 247-417

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration

0.25 mg/mL

More Infomation

Target

Full Name

rabaptin, RAB GTPase binding effector protein 1

Introduction

RABEP1 (Rabaptin, RAB GTPase Binding Effector Protein 1) is a Protein Coding gene. Diseases associated with RABEP1 include Tuberous Sclerosis 2. Among its related pathways are Delta508-CFTR traffic / Sorting endosome formation in CF and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and growth factor activity. An important paralog of this gene is RABEP2.

Entrez Gene ID

Human	9135
Mouse	54189
Rat	54190

UniProt ID

Human	Q15276
Mouse	O35551
Rat	O35550

Alternative Names

Rabaptin, RAB GTPase Binding Effector Protein 1; Renal Carcinoma Antigen NY-REN-17; Rabaptin-5alpha; Rabaptin-4; Rabaptin-5; RAB5EP;

Function

Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane (PubMed:22841712).
Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium (By similarity).

Biological Process

Biological Process apoptotic processIEA:UniProtKB-KW
Biological Process endocytosisManual Assertion Based On ExperimentTAS:ProtInc
Biological Process Golgi to plasma membrane transportISS:UniProtKB
Biological Process membrane fusionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process protein localization to ciliary membraneISS:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW
Biological Process vesicle-mediated transportManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Cytoplasm
Early endosome
Recycling endosome
Cytoplasmic vesicle

PTM

Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-RABEP1 Recombinant Antibody (20/Rabaptin-5)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-RABEP1 Recombinant Antibody (CBCNR-080) (CAT#: CBMAB-R0963-CN)

Mouse Anti-RABEP1 Recombinant Antibody (CBCNR-081) (CAT#: CBMAB-R0964-CN)

Mouse Anti-RABEP1 Recombinant Antibody (3H6) (CAT#: CBMAB-R0962-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry