Mouse Anti-RAD23B Recombinant Antibody (A1411) (CBMAB-AP2992LY)

Name: Mouse Anti-RAD23B Recombinant Antibody (A1411)
SKU: CBMAB-AP2992LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

A1411

Application

ICCIHC, WB

Specificity

Hamster, Human, Monkey, Mouse, Rat

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

Affinity purity

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

RAD23 Homolog B, Nucleotide Excision Repair Protein

Introduction

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2011]

Entrez Gene ID

Human	5887
Mouse	19359
Rat	298012
Monkey	711328
Hamster	101840469

UniProt ID

Human	P54727
Mouse	P54728
Rat	Q4KMA2
Monkey	H9YX93
Hamster	A0A1U7QD35

Alternative Names

RAD23 Homolog B, Nucleotide Excision Repair Protein; XP-C Repair-Complementing Complex 58 KDa Protein; XP-C Repair Complementing Complex 58 KDa; XP-C Repair Complementing Protein; HHR23B; HR23B;

Function

SAB-27219

Biological Process

Biological Process cellular response to interleukin-7IEA:Ensembl
Biological Process nucleotide-excision repairManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process proteasome-mediated ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of proteasomal ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process spermatogenesisIEA:Ensembl

Cellular Location

Nucleus
Cytoplasm
The intracellular distribution is cell cycle dependent. Localized to the nucleus and the cytoplasm during G1 phase. Nuclear levels decrease during S-phase; upon entering mitosis, relocalizes in the cytoplasm without association with chromatin.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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