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Mouse Anti-RAD52 Antibody (11BA5) (CBMAB-1533CQ)

This product is a mouse antibody that recognizes RAD52. The antibody 11BA5 can be used for immunoassay techniques such as: ELISA, WB.
See all RAD52 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
11BA5
Antibody Isotype
IgG1
Application
ELISA, WB

Basic Information

Immunogen
Recombinant full length protein
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
RAD52
Introduction
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. Among its related pathways are DNA Double-Strand Break Repair and DNA Damage Response.
Entrez Gene ID
UniProt ID
Alternative Names
RAD52 homolog (S. cerevisiae); DNA repair protein RAD52 homolog; recombination protein RAD52; rhabdomyosarcoma antigen MU-RMS-40.23;
Function
Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase.
Biological Process
Biological Process cellular response to DNA damage stimulusManual Assertion Based On ExperimentIGI:MGI
Biological Process cellular response to oxidative stressManual Assertion Based On ExperimentIDA:MGI
Biological Process DNA double-strand break processing involved in repair via single-strand annealingManual Assertion Based On ExperimentIDA:MGI
Biological Process DNA recombinase assemblyIEA:InterPro
Biological Process DNA recombinationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process double-strand break repairManual Assertion Based On ExperimentTAS:ProtInc
Biological Process double-strand break repair via homologous recombinationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process double-strand break repair via single-strand annealingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process mitotic recombinationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of nucleotide-excision repairManual Assertion Based On ExperimentIDA:MGI
Cellular Location
Nucleus
PTM
Phosphorylated upon DNA damage by ABL1, and probably by ATM or ATR.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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