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Mouse Anti-RASA2 Recombinant Antibody (0.T.131) (CBMAB-R1464-CN)

This product is a Mouse antibody that recognizes RASA2. The antibody 0.T.131 can be used for immunoassay techniques such as: WB, IP, ICC.
See all RASA2 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Hamster, Cattle
Clone
0.T.131
Antibody Isotype
IgG
Application
WB, IP, ICC

Basic Information

Specificity
Mouse, Rat, Hamster, Cattle
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1 mg/mL

Target

Full Name
RAS P21 Protein Activator 2
Introduction
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Entrez Gene ID
Human5922
Mouse114713
Rat25597
Cattle533491
UniProt ID
HumanQ15283
MouseP58069
RatQ63713
CattleF1N795
Alternative Names
RAS P21 Protein Activator 2; GTPase-Activating Protein 1m; GAP1M; GTPase-Activating Protein Of RAS; Ras GTPase-Activating Protein 2; RASGAP;
Function
Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4).
Biological Process
Biological Process intracellular signal transductionIEA:InterPro
Biological Process negative regulation of Ras protein signal transductionIEA:InterPro
Biological Process regulation of GTPase activityIEA:InterPro
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytoplasm
Cytoplasm, perinuclear region
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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