Mouse Anti-RBAK Recombinant Antibody (CBCNR-274) (CBMAB-R1628-CN)

Name: Mouse Anti-RBAK Recombinant Antibody (CBCNR-274)
SKU: CBMAB-R1628-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBCNR-274

Application

ELISA, WB

Immunogen

RBAK (NP_066986, aa. 51-150) partial recombinant protein with GST tag

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

1× PBS, pH 7.2

More Infomation

Target

Full Name

RB-associated KRAB zinc finger

Introduction

This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011]

Entrez Gene ID

57786

UniProt ID

Q9NYW8

Alternative Names

RB Associated KRAB Zinc Finger; RB-Associated KRAB Repressor; Zinc Finger Protein 769; ZNF769; RB-Associated KRAB Zinc Finger Protein; HRBaK;

Function

May repress E2F-dependent transcription. May promote AR-dependent transcription.

Biological Process

Biological Process negative regulation of transcription, DNA-templatedManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of transcription, DNA-templatedManual Assertion Based On ExperimentTAS:UniProtKB

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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