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Mouse Anti-RBAK Recombinant Antibody (CBCNR-274) (CBMAB-R1628-CN)

This product is a Mouse antibody that recognizes RBAK. The antibody CBCNR-274 can be used for immunoassay techniques such as: ELISA, WB.
See all RBAK antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNR-274
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
RBAK (NP_066986, aa. 51-150) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
1× PBS, pH 7.2

Target

Full Name
RB-associated KRAB zinc finger
Introduction
This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011]
Entrez Gene ID
UniProt ID
Alternative Names
RB Associated KRAB Zinc Finger; RB-Associated KRAB Repressor; Zinc Finger Protein 769; ZNF769; RB-Associated KRAB Zinc Finger Protein; HRBaK;
Function
May repress E2F-dependent transcription. May promote AR-dependent transcription.
Biological Process
Biological Process negative regulation of transcription, DNA-templatedManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of transcription, DNA-templatedManual Assertion Based On ExperimentTAS:UniProtKB
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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