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Mouse Anti-RBMXL2 Recombinant Antibody (6F11) (CBMAB-R1775-CN)

This product is a Mouse antibody that recognizes RBMXL2. The antibody 6F11 can be used for immunoassay techniques such as: ELISA, IF, IHC, WB.
See all RBMXL2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
6F11
Antibody Isotype
IgG1, κ
Application
ELISA, IF, IHC, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa. 1-91 from human HNRNPG-T (NP_055284) with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
RNA Binding Motif Protein, X-Linked Like 2
Introduction
This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. [provided by RefSeq, Jul 2008]
Entrez Gene ID
27288
UniProt ID
O75526
Alternative Names
RNA Binding Motif Protein, X-Linked Like 2; Testis-Specific Heterogeneous Nuclear Ribonucleoprotein G-T; Heterogeneous Nuclear Ribonucleoprotein G T; HnRNP G-T; HNRNPGT; Testes-Specific Heterogenous Nuclear Ribonucleoprotein G-T; RNA-Binding Motif Protein, X-Linked-Like-2; HNRNPG-T; HNRPGT;
Biological Process
mRNA splicing, via spliceosome
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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