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Mouse Anti-RBMY1A1 Recombinant Antibody (CBCNR-323) (CBMAB-R1781-CN)

This product is a Mouse antibody that recognizes RBMY1A1. The antibody CBCNR-323 can be used for immunoassay techniques such as: ELISA.
See all RBMY1A1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNR-323
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
RBMY1A1 (NP_001007527.1, aa. 257-356) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
1× PBS, pH 7.2

Target

Full Name
RNA binding motif protein, Y-linked, family 1, member A1
Introduction
This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. This protein is thought to function as a splicing regulator during spermatogenesis. Multiple closely related paralogs of this gene are found in a gene cluster in the AZFb azoospermia factor region of chromosome Y. Most of these related copies are thought to be pseudogenes, though several likely encode functional proteins. [provided by RefSeq, Mar 2016]
Entrez Gene ID
5940
UniProt ID
P0DJD3
Alternative Names
RNA Binding Motif Protein, Y-Linked, Family 1, Member A1; Y Chromosome RNA Recognition Motif 1; RNA-Binding Motif Protein 2; YRRM1; YRRM2; RBM1; RBM2; RNA-Binding Motif Protein, Y Chromosome, Family 1 Member A1/C; RNA Binding Motif Protein, Y Chromosome, Family 1, Member A1;
Function
RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs.
Biological Process
Biological Process alternative mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIBA:GO_Central
Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of alternative mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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