Mouse Anti-RCAN2 Recombinant Antibody (1A9) (CBMAB-R1917-CN)

Name: Mouse Anti-RCAN2 Recombinant Antibody (1A9)
SKU: CBMAB-R1917-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1A9

Application

Immunogen

RCN2 (H04892.1, aa. 24-317) full-length recombinant protein with GST tag

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Preservative

No preservatives

More Infomation

Target

Full Name

Regulator Of Calcineurin 2

Introduction

This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Entrez Gene ID

10231

UniProt ID

Q14206

Alternative Names

Regulator Of Calcineurin 2; Myocyte-Enriched Calcineurin-Interacting Protein 2; Down Syndrome Critical Region Gene 1-Like 1; Thyroid Hormone-Responsive Protein ZAKI-4; Down Syndrome Candidate Region 1-Like 1; DSCR1L1; MCIP2;

Function

Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

Biological Process

Calcium-mediated signaling

Cellular Location

cytoplasm
nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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