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Mouse Anti-RCAN2 Recombinant Antibody (1A9) (CBMAB-R1917-CN)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1A9
Antibody Isotype
IgG1, κ
Application
WB

Basic Information

Immunogen
RCN2 (H04892.1, aa. 24-317) full-length recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Preservative
No preservatives

Target

Full Name
Regulator Of Calcineurin 2
Introduction
This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Entrez Gene ID
10231
UniProt ID
Q14206
Alternative Names
Regulator Of Calcineurin 2; Myocyte-Enriched Calcineurin-Interacting Protein 2; Down Syndrome Critical Region Gene 1-Like 1; Thyroid Hormone-Responsive Protein ZAKI-4; Down Syndrome Candidate Region 1-Like 1; DSCR1L1; MCIP2;
Function
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
Biological Process
Calcium-mediated signaling
Cellular Location
cytoplasm
nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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