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Mouse Anti-RCBTB1 Recombinant Antibody (1E4) (CBMAB-R1919-CN)

This product is a Mouse antibody that recognizes RCBTB1. The antibody 1E4 can be used for immunoassay techniques such as: ELISA, WB.
See all RCBTB1 antibodies
Published Data
Fig.1 The upregulation of GLP-1R protein expression both in vivo and in vitro due to E4 stimulation.
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Fig.2 The upregulation of GLP-1R protein expression both in vivo and in vitro due to E4 stimulation.
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Fig.3 The upregulation of GLP-1R protein expression both in vivo and in vitro due to E4 stimulation.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
1E4
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa. 2-91 from human RCBTB1 (NP_060661) with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
Introduction
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008]
Entrez Gene ID
55213
UniProt ID
Q8NDN9
Alternative Names
RCC1 And BTB Domain Containing Protein 1; Regulator Of Chromosome Condensation (RCC1) And BTB (POZ) Domain Containing Protein 1; Regulator Of Chromosome Condensation And BTB Domain-Containing Protein 1; Chronic Lymphocytic Leukemia Deletion Region Gene 7 Protein; CLL Deletion Region Gene 7 Protein; CLLD7; GDP/GTP Exchange Factor (GEF)-Like Protein;
Function
May be involved in cell cycle regulation by chromatin remodeling.
Biological Process
Biological Process cell cycleIEA:UniProtKB-KW
Biological Process chromatin organizationIEA:UniProtKB-KW
Cellular Location
Nucleus
Involvement in disease
Retinal dystrophy with or without extraocular anomalies (RDEOA):
An autosomal recessive disease characterized by progressive retinal dystrophy, chorioretinal macular atrophy, reduced cone and rod responses on ERG, and decrease visual acuity. Extraocular anomalies are variably present in some patients and include pulmonary fibrosis, sensorineural hearing loss, and endocrine features such as goiter and primary ovarian insufficiency.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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