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Mouse Anti-RFTN2 Recombinant Antibody (F-7) (CBMAB-R2377-CN)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
F-7
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
Raftlin Family Member 2
Introduction
RFTN2 (Raftlin Family Member 2) is a Protein Coding gene. An important paralog of this gene is RFTN1.
Entrez Gene ID
130132
UniProt ID
Q52LD8
Alternative Names
Raftlin Family Member 2; Raft-Linking Protein 2; C2orf11; Chromosome 2 Open Reading Frame 11; Raftlin-2;
Function
Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling.
Biological Process
Biological Process dsRNA transportIEA:Ensembl
Biological Process response to exogenous dsRNAIEA:Ensembl
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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