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Mouse Anti-RFX1 Recombinant Antibody (D-3) (CBMAB-R2379-CN)

This product is a Mouse antibody that recognizes RFX1. The antibody D-3 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all RFX1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
D-3
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
Regulatory Factor X1
Introduction
This gene encodes a member of the regulatory factor X (RFX) family of transcription factors, which are characterized by a winged-helix DNA-binding domain. The encoded transcription factor contains an N-terminal activation domain and a C-terminal repression domain, and may activate or repress target gene expression depending on cellular context. This transcription factor has been shown to regulate a wide variety of genes involved in immunity and cancer, including the MHC class II genes and genes that may be involved in cancer progression. This gene exhibits altered expression in glioblastoma and the autoimmune disease systemic lupus erythematosis (SLE). [provided by RefSeq, Jul 2016]
Entrez Gene ID
5989
UniProt ID
P22670
Alternative Names
Regulatory Factor X1; Enhancer Factor C; Regulatory Factor X, 1 (Influences HLA Class II Expression); MHC Class II Regulatory Factor RFX; Trans-Acting Regulatory Factor 1; Transcription Factor RFX1;
Function
Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes. Also binds to an inverted repeat (ENH1) required for hepatitis B virus genes expression and to the most upstream element (alpha) of the RPL30 promoter.
Biological Process
Biological Process immune responseManual Assertion Based On ExperimentTAS:ProtInc
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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