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Mouse Anti-RGL1 Recombinant Antibody (2D10) (CBMAB-R2405-CN)

This product is a Mouse antibody that recognizes RGL1. The antibody 2D10 can be used for immunoassay techniques such as: ELISA, IHC, WB.
See all RGL1 antibodies
Published Data
Fig.1 TIPE2 binds the Ras-interacting domain of RGL, and inhibits Ral activation.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
2D10
Antibody Isotype
IgG1, κ
Application
ELISA, IHC, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa. 2-110 from RGL1 (NP_055964) with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
ral guanine nucleotide dissociation stimulator-like 1
Introduction
RGL1 (Ral Guanine Nucleotide Dissociation Stimulator Like 1) is a Protein Coding gene. Diseases associated with RGL1 include Nutritional Optic Neuropathy and Toxic Optic Neuropathy. Among its related pathways are G-protein signaling N-RAS regulation pathway and Metabolism. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and Ral guanyl-nucleotide exchange factor activity. An important paralog of this gene is RALGDS.
Entrez Gene ID
23179
UniProt ID
Q9NZL6
Alternative Names
Ral Guanine Nucleotide Dissociation Stimulator Like 1; RalGDS-Like 1; RGL; Ral Guanine Nucleotide Dissociation Stimulator-Like 1; KIAA0959;
Function
Probable guanine nucleotide exchange factor.
Biological Process
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process small GTPase mediated signal transduction1 PublicationNAS:UniProtKB
Cellular Location
cytosol
plasma membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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