Mouse Anti-RGS13 Recombinant Antibody (CBCNR-449) (CBMAB-R2431-CN)

Name: Mouse Anti-RGS13 Recombinant Antibody (CBCNR-449)
SKU: CBMAB-R2431-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBCNR-449

Application

IHC-P, ELISA, WB

Immunogen

RGS13 (NP_658912.1, aa. 60-159) partial recombinant protein with GST tag

Specificity

Human

Antibody Isotype

IgG2b, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

1× PBS, pH 7.2

More Infomation

Target

Full Name

regulator of G-protein signaling 13

Introduction

The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq, Jul 2008]

Entrez Gene ID

6003

UniProt ID

O14921

Alternative Names

Regulator Of G Protein Signaling 13; Regulator Of G-Protein Signalling 13; Regulator Of G-Protein Signaling 13;

Function

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to both G(i)-alpha and G(q)-alpha (By similarity).

Biological Process

Biological Process G protein-coupled receptor signaling pathwayTAS:Reactome
Biological Process negative regulation of G protein-coupled receptor signaling pathwayIEA:Ensembl

Cellular Location

cytosol
nucleus
plasma membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

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Mouse Anti-RGS13 Recombinant Antibody (G-7) (CAT#: CBMAB-R2432-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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