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Mouse Anti-RGS13 Recombinant Antibody (G-7) (CBMAB-R2432-CN)

This product is a Mouse antibody that recognizes RGS13. The antibody G-7 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all RGS13 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
G-7
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
regulator of G-protein signaling 13
Introduction
The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq, Jul 2008]
Entrez Gene ID
6003
UniProt ID
O14921
Alternative Names
Regulator Of G Protein Signaling 13; Regulator Of G-Protein Signalling 13; Regulator Of G-Protein Signaling 13;
Function
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to both G(i)-alpha and G(q)-alpha (By similarity).
Biological Process
Biological Process G protein-coupled receptor signaling pathwayTAS:Reactome
Biological Process negative regulation of G protein-coupled receptor signaling pathwayIEA:Ensembl
Cellular Location
cytosol
nucleus
plasma membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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