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Mouse Anti-RGS9BP Recombinant Antibody (D7) (CBMAB-1764-CN)

This product is a mouse antibody that recognizes RGS9BP of mouse. The antibody D7 can be used for immunoassay techniques such as: ICC, IP, WB.
See all RGS9BP antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Cattle
Clone
D7
Antibody Isotype
IgG1
Application
ICC, IP, WB

Basic Information

Immunogen
Other Immunogen Type corresponding to RGS9-1. Full length, bacterially expressed RGS9-1
Specificity
Mouse, Cattle
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
99% PBS, 0.1% BSA
Preservative
0.05% Sodium azide
Concentration
1.93 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Regulator Of G Protein Signaling 9 Binding Protein
Introduction
Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. This protein acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation.
Entrez Gene ID
Cattle282338
Mouse243923
UniProt ID
CattleQ8MJG0
MouseQ148R9
Alternative Names
R9AP; Rgs9-1bp
Function
Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation (By similarity).
Biological Process
Biological Process detection of light stimulus involved in visual perceptionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of signal transductionIEA:UniProtKB-KW
Cellular Location
Membrane
Involvement in disease
Prolonged electroretinal response suppression (PERRS):
Characterized by difficulty adjusting to sudden changes in luminance levels mediated by cones.
Topology
Cytoplasmic: 1-210
Helical: 211-231
Extracellular: 232-235
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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