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Mouse Anti-RHBDL2 Recombinant Antibody (2H1) (CBMAB-R2502-CN)

This product is a Mouse antibody that recognizes RHBDL2. The antibody 2H1 can be used for immunoassay techniques such as: ELISA, WB.
See all RHBDL2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2H1
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa. 1-73 from human RHBDL2 (NP_060291) with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
rhomboid, veinlet-like 2 (Drosophila)
Introduction
The protein encoded by this gene is a member of the rhomboid family of integral membrane proteins. This family contains proteins that are related to Drosophila rhomboid protein. Members of this family are found in both prokaryotes and eukaryotes and are thought to function as intramembrane serine proteases. The encoded protein is thought to release soluble growth factors by proteolytic cleavage of certain membrane-bound substrates, including ephrin B2 and ephrin B3. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015]
Entrez Gene ID
54933
UniProt ID
Q9NX52
Alternative Names
Rhomboid Like 2; Rhomboid (Veinlet, Drosophila)-Like 2; Rhomboid-Like Protein 2; RRP2; Rhomboid, Veinlet-Like 2 (Drosophila); Rhomboid-Related Protein 2; Rhomboid, Veinlet-Like 2; Rhomboid Protease 2; EC 3.4.21.105;
Function
Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Known substrate: EFNB3.
Biological Process
Proteolysis
Cellular Location
Rhomboid-related protein 2, C-terminal fragment
Cell membrane
PTM
Proteolytic processing of the proenzyme produces a N-terminal fragment (NTF) and a C-terminal fragment (CTF). The processing is required for activation of the protease.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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