Mouse Anti-RHCG Recombinant Antibody (5A4) (CBMAB-R2506-CN)

Name: Mouse Anti-RHCG Recombinant Antibody (5A4)
SKU: CBMAB-R2506-CN
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

5A4

Application

ELISA, IHC, WB

Immunogen

Partial recombinant corresponding to aa. 418-480 from human RHCG (NP_057405) with GST tag

Specificity

Human, Rat

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

More Infomation

Target

Full Name

Rh family, C glycoprotein

Introduction

RHCG (Rh Family C Glycoprotein) is a Protein Coding gene. Diseases associated with RHCG include Retinohepatoendocrinologic Syndrome and Acute Urate Nephropathy. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include ankyrin binding and ammonium transmembrane transporter activity. An important paralog of this gene is RHBG.

Entrez Gene ID

Human	51458
Rat	293048

UniProt ID

Human	Q9UBD6
Rat	Q7TNN9

Alternative Names

Rh Family C Glycoprotein; Rhesus Blood Group Family Type C Glycoprotein; Rhesus Blood Group, C Glycoprotein; Rh Family Type C Glycoprotein; Tumor-Related Protein DRC2; Rh Glycoprotein Kidney; Rh Type C Glycoprotein; C15orf6;

Function

Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion.

Biological Process

Biological Process amine transport1 PublicationNAS:UniProtKB
Biological Process ammonium homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process ammonium transmembrane transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular ion homeostasisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process epithelial cell differentiation1 PublicationNAS:UniProtKB
Biological Process homeostatic process1 PublicationNAS:UniProtKB
Biological Process regulation of pHIEA:Ensembl
Biological Process transepithelial ammonium transportManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Apical cell membrane
Also detected at the basolateral membrane and in subapical vesicles.

Topology

Cytoplasmic: 1-9
Helical: 10-30
Extracellular: 31-60
Helical: 61-81
Cytoplasmic: 82-85
Helical: 86-106
Extracellular: 107-123
Helical: 124-144
Cytoplasmic: 145-148
Helical: 149-169
Extracellular: 170-177
Helical: 178-200
Cytoplasmic: 201-218
Helical: 219-239
Extracellular: 240-250
Helical: 251-271
Cytoplasmic: 272-281
Helical: 282-302
Extracellular: 303
Helical: 304-324
Cytoplasmic: 325-345
Helical: 346-366
Extracellular: 367-394
Helical: 395-415
Cytoplasmic: 416-479

PTM

N-glycosylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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