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Mouse Anti-RHEBL1 Recombinant Antibody (4G6) (CBMAB-R2513-CN)

This product is a Mouse antibody that recognizes RHEBL1. The antibody 4G6 can be used for immunoassay techniques such as: ELISA, WB.
See all RHEBL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4G6
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa. 87-183 from human RHEBL1 (H27482) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
RHEB Like 1
Introduction
RHEBL1 (RHEB Like 1) is a Protein Coding gene. Diseases associated with RHEBL1 include Renal Clear Cell Carcinoma. Among its related pathways are AMP-activated Protein Kinase (AMPK) Signaling. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RHEB.
Entrez Gene ID
121268
UniProt ID
Q8TAI7
Alternative Names
RHEB Like 1; Ras Homolog Enriched In Brain-Like Protein 1; Ras Homolog Enriched In Brain Like-1 C; Rheb-Like Protein 1; RHEBL1c; RHEB2; Ras Homolog Enriched In Brain Like 1 C; Ras Homolog Enriched In Brain Like 1; GTPase RhebL1;
Function
Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.
Biological Process
Biological Process positive regulation of NF-kappaB transcription factor activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process small GTPase mediated signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process TOR signalingManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Endomembrane system
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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