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Mouse Anti-RHOBTB3 Recombinant Antibody (3A10) (CBMAB-R2559-CN)

This product is a Mouse antibody that recognizes RHOBTB3. The antibody 3A10 can be used for immunoassay techniques such as: ELISA.
See all RHOBTB3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3A10
Antibody Isotype
IgG1, κ
Application
ELISA

Basic Information

Immunogen
Partial recombinant corresponding to aa. 1-100 from RHOBTB3 (NP_055714) with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
Rho-related BTB domain containing 3
Introduction
RHOBTB3 is a member of the evolutionarily conserved RHOBTB subfamily of Rho GTPases. For background information on RHOBTBs, see RHOBTB1 (MIM 607351). [supplied by OMIM, Apr 2004]
Entrez Gene ID
UniProt ID
Alternative Names
Rho Related BTB Domain Containing 3; Rho-Related BTB Domain Containing 3; EC 3.6.1.-; KIAA0878;
Function
Rab9-regulated ATPase required for endosome to Golgi transport. Involved in transport vesicle docking at the Golgi complex, possibly by participating in release M6PRBP1/TIP47 from vesicles to permit their efficient docking and fusion at the Golgi. Specifically binds Rab9, but not other Rab proteins. Has low intrinsic ATPase activity due to autoinhibition, which is relieved by Rab9.
Biological Process
Biological Process actin filament organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cortical cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process establishment or maintenance of cell polarityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process male gonad developmentIEA:Ensembl
Biological Process regulation of actin cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of cell shapeManual Assertion Based On ExperimentIBA:GO_Central
Biological Process retrograde transport, endosome to GolgiManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process small GTPase mediated signal transductionIEA:InterPro
Cellular Location
Golgi apparatus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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