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Mouse Anti-RHPN2 Recombinant Antibody (1C5) (CBMAB-R2615-CN)

This product is a Mouse antibody that recognizes RHPN2. The antibody 1C5 can be used for immunoassay techniques such as: ELISA.
See all RHPN2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C5
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
RHPN2 (H36447.1, aa. 1-686) full-length recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Preservative
No preservatives

Target

Full Name
rhophilin, Rho GTPase binding protein 2
Introduction
This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009]
Entrez Gene ID
85415
UniProt ID
Q8IUC4
Alternative Names
Rhophilin Rho GTPase Binding Protein 2; 76 KDa RhoB Effector Protein; GTP-Rho-Binding Protein 2; P76RBE; Rhophilin-Like Rho-GTPase Binding Protein; Rhophilin-2; RHOBP;
Function
Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity.
Biological Process
Biological Process glomerular filtrationIEA:Ensembl
Biological Process negative regulation of stress fiber assemblyManual Assertion Based On ExperimentIDA:MGI
Biological Process signal transductionIEA:InterPro
Cellular Location
Cytoplasm, perinuclear region
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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