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Mouse Anti-RIPPLY3 Recombinant Antibody (1D1) (CBMAB-D2231-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Ripply Transcriptional Repressor 3 (RIPPLY3). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all RIPPLY3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1D1
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
DSCR6 (NP_061835.1, 1 a.a. ~ 190 a.a) full-length recombinant protein with GST tag. The immunogen sequence: MEPEAAAGAR KARGRGCHCP GDAPWRPPPP RGPESPAPWR PWIQTPGDAE LTRTGRPLEP RADQHTFGSK GAFGFQHPVR VYLPMSKRQE YLRSSGEQVL ASFPVQATID FYDDESTESA SEAEEPEEGP PPLHLLPQEV GGRQENGPGG KGRDQGINQG QRSSGGGDHW GEGPLPQGVS SRGGKCSSSK
Specificity
Human
Antibody Isotype
IgG2b, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Ripply Transcriptional Repressor 3
Introduction
RIPPLY3 (Ripply Transcriptional Repressor 3) is a protein coding gene. Diseases associated with RIPPLY3 include Down Syndrome and Velocardiofacial Syndrome.
Entrez Gene ID
53820
UniProt ID
P57055
Alternative Names
Ripply Transcriptional Repressor 3; Down Syndrome Critical Region Protein 6; Down Syndrome Critical Region Gene 6; DSCR6; Ripply3 Homolog (Zebrafish); Protein Ripply3; Ripply3 Homolog;
Function
Acts as a transcriptional corepressor. Negative regulator of the transcriptional activity of TBX1. Plays a role in the development of the pharyngeal apparatus and derivatives (By similarity).
Biological Process
Biological Process cell population proliferationIEA:Ensembl
Biological Process embryonic pattern specificationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process heart developmentIEA:Ensembl
Biological Process negative regulation of cell population proliferationIEA:Ensembl
Biological Process negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process pharyngeal system developmentIEA:Ensembl
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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