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Mouse Anti-RMC1 Recombinant Antibody (CBFYM-3089) (CBMAB-M3285-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-3089
Antibody Isotype
IgG2a
Application
WB, FC

Basic Information

Immunogen
Full length human recombinant protein of human C18orf8(NP_037458) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Regulator Of MON1-CCZ1
Introduction
This gene encodes a colon cancer associated protein.
Entrez Gene ID
29919
UniProt ID
Q96DM3
Alternative Names
Regulator Of MON1-CCZ1; C18orf8; Colon Cancer-Associated Protein Mic1; Chromosome 18 Open Reading Frame 8; WD Repeat Domain 98; MIC-1; MIC1
Function
Componement of the CCZ1-MON1 RAB7A guanine exchange factor (GEF). Acts as a positive regulator of CCZ1-MON1A/B function necessary for endosomal/autophagic flux and efficient RAB7A localization (PubMed:29038162).
Biological Process
Biological Process autophagyIEA:UniProtKB-KW
Biological Process regulation of autophagyManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Lysosome membrane
Late endosome membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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