Mouse Anti-RNF114 Recombinant Antibody (4G3-1A10) (CBMAB-Z0499-WJ)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
In turn, participates in the regulation of many biological processes including cell cycle, apoptosis, osteoclastogenesis as well as innate or adaptive immunity (PubMed:25165885, PubMed:28708287).
Acts as negative regulator of NF-kappa-B-dependent transcription by promoting the ubiquitination and stabilization of the NF-kappa-B inhibitor TNFAIP3 (PubMed:25165885).
May promote the ubiquitination of TRAF6 as well (PubMed:28708287).
Acts also as a negative regulator of T-cell activation (PubMed:25165885).
Inhibits cellular dsRNA responses and interferon production by targeting MAVS component for proteasomal degradation (PubMed:25165885).
Ubiquitinates the CDK inhibitor CDKN1A leading to its degradationand probably also CDKN1B and CDKN1C (PubMed:23645206).
This activity stimulates cell cycle G1-to-S phase transition and suppresses cellular senescence. May play a role in spermatogenesis.
Biological Process protein polyubiquitinationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process spermatogenesisIEA:UniProtKB-KW
Biological Process ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Nucleus
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols
Alternative Versions
Mouse Anti-RNF114 Recombinant Antibody (4G3-1A10) (CAT#: CBMAB-A10168-LY)
Antibody Pairs
RNF114 Matched Antibody Pair (1004) (CAT#: APMAB-1004LY)
Related Products
Mouse Anti-RNF114 Recombinant Antibody (S2) (CAT#: CBMAB-A10169-LY)
RNF114 Matched Antibody Pair (1004) (CAT#: APMAB-1004LY)
Mouse Anti-RNF114 Recombinant Antibody (3347C1a) (CAT#: CBMAB-Z0500-WJ)
Mouse Anti-RNF114 Recombinant Antibody (4G3-1A10) (CAT#: CBMAB-A10168-LY)
Mouse Anti-RNF114 Recombinant Antibody (CBWJZ-193) (CAT#: CBMAB-Z0501-WJ)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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