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Mouse Anti-RNF17 Recombinant Antibody (1E3) (CBMAB-R2963-CN)

This product is a Mouse antibody that recognizes RNF17. The antibody 1E3 can be used for immunoassay techniques such as: ELISA, WB.
See all RNF17 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1E3
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa. 30-140 from human RNF17 (NP_112567) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
RNF17
Introduction
This gene is similar to a mouse gene that encodes a testis-specific protein containing a RING finger domain. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, May 2010]
Entrez Gene ID
UniProt ID
Alternative Names
Ring Finger Protein 17; Tudor Domain-Containing Protein 4; Spermatogenesis Associated 23; Tudor Domain Containing 4; TDRD4; SPATA23; Mmip-2;
Function
Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad-MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity).
Biological Process
Spermatid development
Cellular Location
Cytoplasm
Nucleus
Predominantly found in the cytoplasm. Component of a nuage in male germ cells (an electron-dense spherical cytoplasmic body present in late pachytene and diplotene spermatocytes and in elonging spermatids) (By similarity).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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