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Mouse Anti-RPLP1 Recombinant Antibody (CBCNR-728) (CBMAB-R3406-CN)

This product is a Mouse antibody that recognizes RPLP1. The antibody CBCNR-728 can be used for immunoassay techniques such as: IF, WB, ELISA.
See all RPLP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNR-728
Antibody Isotype
IgG2a, κ
Application
IF, WB, ELISA

Basic Information

Immunogen
RPLP1 (NP_000994.1, aa. 1-114) full-length recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
1× PBS, pH 7.2

Target

Full Name
ribosomal protein, large, P1
Introduction
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P2. The P1 protein can interact with P0 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Two alternatively spliced transcript variants that encode different proteins have been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Entrez Gene ID
6176
UniProt ID
P05386
Alternative Names
Ribosomal Protein Lateral Stalk Subunit P1; Large Ribosomal Subunit Protein P1; Ribosomal Protein, Large, P1; Acidic Ribosomal Phosphoprotein P1; 0S Acidic Ribosomal Protein P1; RPP1; RRP1; LP1; P1;
Function
Plays an important role in the elongation step of protein synthesis.
Biological Process
Biological Process cytoplasmic translationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process translation1 PublicationNAS:UniProtKB
Biological Process translational elongationIEA:InterPro
Cellular Location
cytoplasm
cytosol
cytosolic large ribosomal subunit
cytosolic ribosome
focal adhesion
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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