Mouse Anti-RPS2 Recombinant Antibody (3G6) (CBMAB-R3465-CN)

Name: Mouse Anti-RPS2 Recombinant Antibody (3G6)
SKU: CBMAB-R3465-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

3G6

Application

ELISA, IF, IHC, WB

Immunogen

Partial recombinant corresponding to aa. 198-294 from human RPS2 (NP_002943) with GST tag

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

More Infomation

Target

Full Name

ribosomal protein S2

Introduction

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S5P family of ribosomal proteins. It is located in the cytoplasm. This gene shares sequence similarity with mouse LLRep3. It is co-transcribed with the small nucleolar RNA gene U64, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Entrez Gene ID

6187

UniProt ID

P15880

Alternative Names

Ribosomal Protein S2; Small Ribosomal Subunit Protein US5; 40S Ribosomal Protein S4; Protein LLRep3; 40S Ribosomal Protein S2; OK/KNS-Cl.6; LLREP3; RPS4; S2;

Function

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.

Biological Process

Biological Process cytoplasmic translation1 PublicationIC:FlyBase
Biological Process positive regulation of ubiquitin-protein transferase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process translationManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

cytoplasm
cytosol
cytosolic ribosome
cytosolic small ribosomal subunit
extracellular exosome
focal adhesion
membrane
nucleoplasm
nucleus

PTM

Citrullinated by PADI4 in the Arg/Gly-rich region.
Asymmetric arginine dimethylation by PRMT3 ^oCcurs at multiple sites in the Arg/Gly-rich region.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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