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Mouse Anti-RPS27 Recombinant Antibody (CBT1101) (V2LY-0625-LY3034)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT1101
Antibody Isotype
IgG
Application
IHC-P, IF, ELISA

Basic Information

Immunogen
Purified recombinant fragment of Ribosomal Protein S27 expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
ELISA1:10,000
IHC1:200-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Buffer
BSA, Glycerol
Preservative
Sodium azide
Concentration
Batch dependent
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Ribosomal Protein S27
Entrez Gene ID
6232
Function
Component of the small ribosomal subunit (PubMed:8706699).
Required for proper rRNA processing and maturation of 18S rRNAs (PubMed:25424902).
Biological Process
Biological Process cytoplasmic translation1 PublicationIC:FlyBase
Biological Process ribosomal small subunit assemblyManual Assertion Based On ExperimentIBA:GO_Central
Biological Process rRNA processingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process translation1 PublicationNAS:UniProtKB
Cellular Location
cytosol
cytosolic ribosome
cytosolic small ribosomal subunit
nucleoplasm
nucleus
postsynaptic density
ribosome
Involvement in disease
Diamond-Blackfan anemia 17 (DBA17):
A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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