Mouse Anti-RPS6KC1 Recombinant Antibody (10F11) (CBMAB-R3591-CN)

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Basic Information

Host Animal
Mouse
Clone
10F11
Application
WB, IHC
Immunogen
Human recombinant protein fragment corresponding to aa. 1-305 of human RPS6KC1 (NP_036556) produced in E.coli
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
More Infomation

Target

Full Name
ribosomal protein S6 kinase, 52kDa, polypeptide 1
Introduction
Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. [provided by RefSeq, Mar 2017]
Entrez Gene ID
UniProt ID
Alternative Names
Ribosomal Protein S6 Kinase C1; Ribosomal S6 Kinase-Like Protein With Two PSK Domains 118 KDa Protein; 52 KDa Ribosomal Protein S6 Kinase; SPHK1-Binding Protein; S6K-Delta-1; RPK118; Ribosomal Protein S6 Kinase, 52kDa, Polypeptide 1;
Function
May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell (PubMed:12077123).
Plays a role in the recruitment of PRDX3 to early endosomes (PubMed:15750338).
Biological Process
Biological Process protein phosphorylationIEA:InterPro
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytoplasm
Membrane
Early endosome
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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