Mouse Anti-RRAS Recombinant Antibody (2E12) (CBMAB-R3643-CN)

Name: Mouse Anti-RRAS Recombinant Antibody (2E12)
SKU: CBMAB-R3643-CN
Rating: 5 (1 reviews)

See all RRAS antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

2E12

Application

ELISA, IP, WB

Immunogen

Partial recombinant corresponding to aa. 109-218 from human RRAS (H16286a) with GST tag

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

More Infomation

Target

Full Name

RAS Related

Introduction

The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015]

Entrez Gene ID

6237

UniProt ID

P10301

Alternative Names

RAS Related; Related RAS Viral (R-Ras) Oncogene Homolog; Oncogene RRAS; P23; Ras Family Small GTP Binding Protein R-Ras; Ras-Related Protein R-Ras; R-Ras;

Function

Regulates the organization of the actin cytoskeleton (PubMed:16537651, PubMed:18270267).
With OSPBL3, modulates integrin beta-1 (ITGB1) activity (PubMed:18270267).

Biological Process

Biological Process face morphogenesisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process leukocyte differentiationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of Schwann cell migrationIEA:Ensembl
Biological Process positive regulation of angiogenesisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of endothelial cell migrationManual Assertion Based On ExperimentIMP:CACAO
Biological Process positive regulation of endothelial cell-matrix adhesion via fibronectinManual Assertion Based On ExperimentIMP:CACAO
Biological Process positive regulation of vasculogenesisManual Assertion Based On ExperimentIMP:CACAO
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of ERK1 and ERK2 cascadeManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of protein kinase B signalingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process Schwann cell migrationIEA:Ensembl

Cellular Location

Cell membrane
Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).

PTM

S-palmitoylated by ZDHHC19, leading to increased association with membranes and with rafts/caveolae as well as enhanced cell viability.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-RRAS Recombinant Antibody (2E12)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-RRAS Recombinant Antibody (CBCNR-798) (CAT#: CBMAB-R3647-CN)

Mouse Anti-RRAS Recombinant Antibody (CBCNR-797) (CAT#: CBMAB-R3646-CN)

Mouse Anti-RRAS Recombinant Antibody (CBCNR-799) (CAT#: CBMAB-R3648-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry