Mouse Anti-RRP9 Recombinant Antibody (C-7) (CBMAB-R3708-CN)

Name: Mouse Anti-RRP9 Recombinant Antibody (C-7)
SKU: CBMAB-R3708-CN
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

C-7

Application

WB, IP, IF, ELISA

Specificity

Human

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

Ribosomal RNA Processing 9, U3 Small Nucleolar RNA Binding Protein

Introduction

This gene encodes a member of the WD-repeat protein family. The encoded protein is a component of the nucleolar small nuclear ribonucleoprotein particle (snoRNP) and is essential for 18s rRNA processing during ribosome synthesis. It contains seven WD domains required for nucleolar localization and specific interaction with the U3 small nucleolar RNA (U3 snoRNA). [provided by RefSeq, Oct 2012]

Entrez Gene ID

9136

UniProt ID

O43818

Alternative Names

Ribosomal RNA Processing 9, U3 Small Nucleolar RNA Binding Protein; U3 Small Nucleolar Ribonucleoprotein-Associated 55 KDa Protein; RNA, U3 Small Nucleolar Interacting Protein 2; RRP9 Homolog; RNU3IP2; U3-55K; Ribosomal RNA Processing 9, Small Subunit (SSU) Processome Component, Homolog (Yeast);

Function

Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA (pre-rRNA).

Biological Process

rRNA processing

Cellular Location

Nucleus, nucleolus

PTM

Acetylation at Lys-12 and Lys-25 by KAT2B/PCAF under stress impairs pre-rRNA processing (PubMed:26867678).
Deacetylation by SIRT7 enhances RRP9-binding to U3 snoRNA, which is a prerequisite for pre-rRNA processing (PubMed:26867678).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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