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Mouse Anti-S100A7 Recombinant Antibody (47C1068) (CBMAB-P3630-YC)

Provided herein is a Mouse monoclonal antibody against Human S100 Calcium Binding Protein A7. The antibody can be used for immunoassay techniques, such as WB, IP, IHC-P, IHC-Fr, FC, ICC, IF.
See all S100A7 antibodies
Published Data
Fig.1 Effect of LPS and IL-22 on S100A7, S100A8, and S100A9 protein production.
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Fig.2 RHE were fixed and embedded in paraffin. Four-micrometer vertical sections were stained with H&E or reacted with anti-S100A7 mAb and then photographed under a microscope.
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Fig.3 Transwell migration and Matrigel invasion assays were performed in C33A cells.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
47C1068
Antibody Isotype
IgG1
Application
WB, IP, IHC-P, IHC-Fr, FC, ICC, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
S100 Calcium Binding Protein A7
Introduction
S100A7 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.
Entrez Gene ID
6278
UniProt ID
P31151
Alternative Names
S100 Calcium Binding Protein A7; S100A7c; PSOR1; S100 Calcium-Binding Protein A7 (Psoriasin 1); S100 Calcium Binding Protein A7 (Psoriasin 1); S100 Calcium-Binding Protein A7; Protein S100-A7; Psoriasin 1; Psoriasin;
Function
Biological Process angiogenesis1 PublicationNAS:UniProtKB
Biological Process antimicrobial humoral immune response mediated by antimicrobial peptideManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process defense response to Gram-negative bacteriumManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process epidermis developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process innate immune response1 PublicationNAS:UniProtKB
Biological Process keratinocyte differentiation1 PublicationNAS:UniProtKB
Biological Process positive regulation of ERK1 and ERK2 cascadeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of granulocyte chemotaxisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of monocyte chemotaxisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of T cell chemotaxisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process response to lipopolysaccharideManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process response to reactive oxygen speciesManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process sequestering of metal ionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process
Cytoplasm
Secreted
Secreted by a non-classical secretory pathway.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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