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Mouse Anti-SALL2 (AA 1-199) Recombinant Antibody (CBXS-0115) (CBMAB-S3110-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-0115
Antibody Isotype
IgG2a
Application
ELISA, IHC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-199

Target

Full Name
Spalt Like Transcription Factor 2
Introduction
This gene encodes a protein containing multiple zinc finger domains. The encoded protein functions in optical fissure closure during development of the eye in the embryo. Mutations in this gene are associated with ocular coloboma.
Entrez Gene ID
6297
UniProt ID
Q9Y467
Alternative Names
Spalt Like Transcription Factor 2; Zinc Finger Protein Spalt-2; Zinc Finger Protein SALL2; Zinc Finger Protein 795; ZNF795; HSAL2; Sal-2; Sal (Drosophila)-Like 2;
Function
Probable transcription factor that plays a role in eye development before, during, and after optic fissure closure.
Biological Process
Biological Process eye developmentManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIMP:NTNU_SB
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
Involvement in disease
Coloboma, ocular, autosomal recessive (COAR):
An ocular anomaly resulting from abnormal morphogenesis of the optic cup and stalk, and incomplete fusion of the fetal intra-ocular fissure during gestation. The clinical presentation is variable. Some individuals may present with minimal defects in the anterior iris leaf without other ocular defects. More complex malformations create a combination of iris, uveoretinal and/or optic nerve defects without or with microphthalmia or even anophthalmia.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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