Mouse Anti-SALL2 (AA 1-199) Recombinant Antibody (CBXS-0115) (CBMAB-S3110-CQ)

Name: Mouse Anti-SALL2 (AA 1-199) Recombinant Antibody (CBXS-0115)
SKU: CBMAB-S3110-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-0115

Application

ELISA, IHC, WB

Specificity

Human

Antibody Isotype

IgG2a

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 1-199

More Infomation

Target

Full Name

Spalt Like Transcription Factor 2

Introduction

This gene encodes a protein containing multiple zinc finger domains. The encoded protein functions in optical fissure closure during development of the eye in the embryo. Mutations in this gene are associated with ocular coloboma.

Entrez Gene ID

6297

UniProt ID

Q9Y467

Alternative Names

Spalt Like Transcription Factor 2; Zinc Finger Protein Spalt-2; Zinc Finger Protein SALL2; Zinc Finger Protein 795; ZNF795; HSAL2; Sal-2; Sal (Drosophila)-Like 2;

Function

Probable transcription factor that plays a role in eye development before, during, and after optic fissure closure.

Biological Process

Biological Process eye developmentManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIMP:NTNU_SB
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

Involvement in disease

Coloboma, ocular, autosomal recessive (COAR):
An ocular anomaly resulting from abnormal morphogenesis of the optic cup and stalk, and incomplete fusion of the fetal intra-ocular fissure during gestation. The clinical presentation is variable. Some individuals may present with minimal defects in the anterior iris leaf without other ocular defects. More complex malformations create a combination of iris, uveoretinal and/or optic nerve defects without or with microphthalmia or even anophthalmia.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

SALL2 Matched Antibody Pair (1040) (CAT#: APMAB-1040LY)

Related Products

Mouse Anti-SALL2 Recombinant Antibody (CBXS-5614) (CAT#: CBMAB-S0492-CQ)

SALL2 Matched Antibody Pair (1040) (CAT#: APMAB-1040LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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