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Mouse Anti-SALL3 Recombinant Antibody (CBXS-2040) (CBMAB-S4807-CQ)


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Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBXS-2040
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Spalt Like Transcription Factor 3
Introduction
This gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis.
Entrez Gene ID
Human27164
Mouse20689
Rat364910
UniProt ID
HumanQ9BXA9
MouseQ62255
RatD4A024
Alternative Names
Spalt Like Transcription Factor 3; Zinc Finger Protein 796; ZNF796; HSALL3; C2H2 Zinc Finger Protein SALL3; Spalt-Like Zinc Finger Protein;
Function
Probable transcription factor.
Biological Process
Regulation of transcription by RNA polymerase II
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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