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Mouse Anti-SCARA3 Recombinant Antibody (CBXS-3000) (CBMAB-S5746-CQ)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBXS-3000
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa316-416 from human SCARA3 (NP_057324) with GST tag
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
scavenger receptor class A, member 3
Introduction
This gene encodes a macrophage scavenger receptor-like protein. This protein has been shown to deplete reactive oxygen species, and thus play an important role in protecting cells from oxidative stress. The expression of this gene is induced by oxidative stress. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Entrez Gene ID
Human51435
Mouse219151
Rat364405
UniProt ID
HumanQ6AZY7
MouseQ8C850
RatD3ZPA7
Alternative Names
Scavenger Receptor Class A Member 3; Cellular Stress Response Gene Protein; Macrophage Scavenger Receptor-Like 1; CSR; Scavenger Receptor Class A, Member 3; Cellular Stress Response Protein;
Function
Seems to protect cells by scavenging oxidative molecules or harmful products of oxidation.
Biological Process
Biological Process response to oxidative stressManual Assertion Based On ExperimentTAS:ProtInc
Biological Process UV protectionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Endoplasmic reticulum membrane
Golgi apparatus membrane
Endoplasmic reticulum and/or Golgi.
Topology
Cytoplasmic: 1-56
Helical: 57-77
Extracellular: 78-606
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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