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Mouse Anti-SCML2 Monoclonal Antibody (1D12) (CBMAB-0084-LY)

This product is mouse monoclonal antibody recognizes SCML2 of human. The antibody 1D12 immunoassay techniques such as: IP, ELISA, WB.
See all SCML2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1D12
Antibody Isotype
IgG2c
Application
IP, ELISA, WB

Basic Information

Immunogen
Recombinant peptide (Full Length)
Specificity
Human
Antibody Isotype
IgG2c
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Scm Polycomb Group Protein Like 2
Introduction
SCML2 (sex comb on midleg-like 2) is a constituent of the Polycomb repressive complex 1, a large multiprotein assembly required for the repression of developmental control genes.
SCML proteins contain two N terminal 100-aa malignant brain tumor (MBT) repeats that also occur in three or four copies in other proteins. We have previously determined the structure of the MBT repeats of SCML2 and have shown that they are similar in structure to chromodomains, suggesting that they may also bind to modified histones.
Entrez Gene ID
UniProt ID
Function
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity).
Biological Process
Biological Process anatomical structure morphogenesisManual Assertion Based On ExperimentIMP:GO_Central
Biological Process negative regulation of DNA-templated transcriptionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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