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Rat Anti-SERPINA1A Recombinant Antibody (CBXS-1960) (CBMAB-S4736-CQ)

This product is a rat antibody that recognizes SERPINA1A. The antibody CBXS-1960 can be used for immunoassay techniques such as: WB.
See all SERPINA1A antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBXS-1960
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
NS0-derived recombinant mouse Serpin A1a, Met1-Lys413, Accession # P07758
Specificity
Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
serine (or cysteine) peptidase inhibitor, clade A, member 1A
Introduction
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.
Entrez Gene ID
20700
UniProt ID
A0A0A0MQA3
Alternative Names
Aat-2; Aat2; Dom1; PI1; Spi1-1; Spi1-3
Function
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin.
Biological Process
Biological Process acute-phase responseIEA:UniProtKB-KW
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of serine-type endopeptidase activityISO:MGI
Biological Process protein N-linked glycosylationManual Assertion Based On ExperimentIDA:MGI
Biological Process response to chromateISO:MGI
Biological Process response to cytokineManual Assertion Based On ExperimentIDA:MGI
Biological Process response to lead ionISO:MGI
Biological Process response to methanolISO:MGI
Biological Process response to peptide hormoneManual Assertion Based On ExperimentIDA:MGI
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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