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Armenian Hamster Anti-SERPINA3G Recombinant Antibody (MoFo29.2) (CBMAB-S0337-CQ)

This product is a Armenian hamster antibody that recognizes SERPINA3G. The antibody MoFo29.2 can be used for immunoassay techniques such as: WB, ELISA, IHC, IF, IHC-P.
See all SERPINA3G antibodies

Summary

Host Animal
Armenian Hamster
Specificity
Hamster, Human, Mouse
Clone
MoFo29.2
Antibody Isotype
IgG2b
Application
WB, ELISA, IHC, IF, IHC-P

Basic Information

Immunogen
Synthetic peptide corresponding to residues N(418)-(436) of hamster Spi2A protein
Specificity
Hamster, Human, Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
serine (or cysteine) peptidase inhibitor, clade A, member 3G
Entrez Gene ID
20715
UniProt ID
Q5I2A0
Alternative Names
2A2; spi2; Spi2A; Spi2-1; AI119734; Spi2/eb.1
Function
Serine and cysteine protease inhibitor. Can inhibit lysosomal papain-like proteases including the cathepsins B, G, H, K, L and V. Ineffective against elastase, granzyme A, granzyme B, or caspases 3, 8 or 9. Inhibition of cytoplasmic cathepsin B following release from the lysosome may protect cells from apoptosis. This may facilitate the survival of progenitor T-cells and the subsequent development of long term memory CD8 T-cells.
Biological Process
Biological Process adaptive immune responseIEA:UniProtKB-KW
Biological Process apoptotic processIEA:UniProtKB-KW
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to cytokineManual Assertion Based On ExperimentIDA:MGI
Biological Process response to peptide hormoneManual Assertion Based On ExperimentIDA:MGI
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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