Armenian Hamster Anti-SERPINA3G Recombinant Antibody (MoFo29.2) (CBMAB-S0337-CQ)

Name: Armenian Hamster Anti-SERPINA3G Recombinant Antibody (MoFo29.2)
SKU: CBMAB-S0337-CQ
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Armenian Hamster

Clone

MoFo29.2

Application

WB, ELISA, IHC, IF, IHC-P

Immunogen

Synthetic peptide corresponding to residues N(418)-(436) of hamster Spi2A protein

Specificity

Hamster, Human, Mouse

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration

1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

serine (or cysteine) peptidase inhibitor, clade A, member 3G

Entrez Gene ID

20715

UniProt ID

Q5I2A0

Alternative Names

2A2; spi2; Spi2A; Spi2-1; AI119734; Spi2/eb.1

Function

Serine and cysteine protease inhibitor. Can inhibit lysosomal papain-like proteases including the cathepsins B, G, H, K, L and V. Ineffective against elastase, granzyme A, granzyme B, or caspases 3, 8 or 9. Inhibition of cytoplasmic cathepsin B following release from the lysosome may protect cells from apoptosis. This may facilitate the survival of progenitor T-cells and the subsequent development of long term memory CD8 T-cells.

Biological Process

Biological Process adaptive immune responseIEA:UniProtKB-KW
Biological Process apoptotic processIEA:UniProtKB-KW
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to cytokineManual Assertion Based On ExperimentIDA:MGI
Biological Process response to peptide hormoneManual Assertion Based On ExperimentIDA:MGI

Cellular Location

Cytoplasm
Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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