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Mouse Anti-SERPINB9 Recombinant Antibody (1F5) (CBMAB-A8001-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1F5
Antibody Isotype
IgG2a, κ
Application
IHC, ELISA

Basic Information

Immunogen
SERPINB9 (NP_004146, 279 a.a. ~ 375 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
serpin peptidase inhibitor, clade B (ovalbumin), member 9
Introduction
PI9 belongs to the large superfamily of serine proteinase inhibitors (serpins), which bind to and inactivate serine proteinases. These interactions are involved in many cellular processes, including coagulation, fibrinolysis, complement fixation, matrix remodeling, and apoptosis (Sprecher et al., 1995 [PubMed 8530382]).[supplied by OMIM
Entrez Gene ID
5272
UniProt ID
P50453
Alternative Names
CAP-3; CAP3; PI9
Function
Granzyme B inhibitor.
Biological Process
Biological Process cellular response to estrogen stimulusManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process immune responseManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process mast cell mediated immunityManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process negative regulation of apoptotic processManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protection from natural killer cell mediated cytotoxicityManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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