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Mouse Anti-SHARPIN Monoclonal Antibody (1A8) (CBMAB-0098-LY)

This product is mouse monoclonal antibody recognizes SHARPIN of human. The antibody 1A8 immunoassay techniques such as: IP, MA, WB.
Host Species
Mouse
Application
IP, MA, WB
Immunogen
Recombinant peptide (Full Length)
Antibody Isotype
IgG2a
Specificity
Human
Clone
1A8
Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
SHARPIN is a ubiquitin-binding and ubiquitin-like-domain-containing protein which, when mutated in mice, results in immune system disorders and multi-organ inflammation1,2. More than that, SHARPIN deficiency leads to rapid cell death upon tumor-necrosis factor a (TNF-a) stimulation via FADD and caspase-8-dependent pathways. SHARPIN thus activates NFkB and inhibits apoptosis via distinct pathways in vivo.
Alternative Name
DKFZP434N1923; SIPL1
Entrez Gene ID
UniProt ID
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For research use only. Not intended for any clinical use.
Cat CBMAB-0098-LY
Conjugates
Size
Price $
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Second antibody and isotype control